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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHX
All Species:
8.48
Human Site:
S162
Identified Species:
13.33
UniProt:
O00330
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00330
NP_001128496.1
501
54122
S162
K
P
S
E
P
R
P
S
P
E
P
Q
I
S
I
Chimpanzee
Pan troglodytes
XP_001149489
501
54051
S162
K
P
S
E
P
R
P
S
P
E
P
Q
I
S
I
Rhesus Macaque
Macaca mulatta
XP_001109997
446
48686
I131
L
G
S
L
I
G
L
I
V
E
E
G
E
D
W
Dog
Lupus familis
XP_533153
501
54075
S162
K
P
S
V
P
S
P
S
P
E
P
Q
I
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKZ9
501
53981
P162
K
P
P
A
P
T
Q
P
S
P
Q
P
Q
I
P
Rat
Rattus norvegicus
P08461
632
67147
A292
E
K
Q
E
D
I
A
A
F
A
D
Y
R
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026358
502
53201
P161
V
T
S
T
P
A
G
P
S
V
S
A
P
P
K
Frog
Xenopus laevis
NP_001087423
478
50485
A147
V
A
A
A
T
K
I
A
N
V
A
P
V
A
K
Zebra Danio
Brachydanio rerio
NP_956854
490
51982
V155
E
I
P
A
L
E
P
V
T
P
P
T
A
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624025
598
64649
V261
K
P
T
A
P
S
G
V
T
P
E
V
V
P
V
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
G174
D
D
G
A
S
S
G
G
S
A
P
A
A
E
K
Sea Urchin
Strong. purpuratus
XP_001177721
482
51019
S149
P
T
Q
A
A
P
T
S
T
G
D
S
P
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WQF7
637
68844
E259
D
K
A
T
L
E
F
E
S
L
E
E
G
Y
L
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
A152
E
K
K
Q
E
A
P
A
E
E
T
K
T
S
A
Red Bread Mold
Neurospora crassa
P20285
458
48601
E143
P
K
D
E
P
K
N
E
S
T
A
S
A
P
T
Conservation
Percent
Protein Identity:
100
99.5
87
90.2
N.A.
85.2
34.4
N.A.
N.A.
72.1
58.8
58
N.A.
N.A.
36.4
37.2
47.3
Protein Similarity:
100
99.8
87.6
93.2
N.A.
91.4
49.6
N.A.
N.A.
82
73.4
73
N.A.
N.A.
51.6
56.7
63
P-Site Identity:
100
100
13.3
80
N.A.
20
6.6
N.A.
N.A.
13.3
0
13.3
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
100
100
13.3
80
N.A.
20
20
N.A.
N.A.
13.3
33.3
33.3
N.A.
N.A.
40
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
32.7
34.7
Protein Similarity:
N.A.
N.A.
N.A.
48.9
51.9
51.1
P-Site Identity:
N.A.
N.A.
N.A.
0
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
40
7
14
7
20
0
14
14
14
20
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
7
0
7
0
0
0
0
0
14
0
0
7
0
% D
% Glu:
20
0
0
27
7
14
0
14
7
34
20
7
7
7
0
% E
% Phe:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
7
20
7
0
7
0
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
7
7
7
0
0
0
0
20
7
14
% I
% Lys:
34
27
7
0
0
14
0
0
0
0
0
7
0
7
20
% K
% Leu:
7
0
0
7
14
0
7
0
0
7
0
0
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% N
% Pro:
14
34
14
0
47
7
34
14
20
20
34
14
14
27
7
% P
% Gln:
0
0
14
7
0
0
7
0
0
0
7
20
7
0
7
% Q
% Arg:
0
0
0
0
0
14
0
0
0
0
0
0
7
0
0
% R
% Ser:
0
0
34
0
7
20
0
27
34
0
7
14
0
27
0
% S
% Thr:
0
14
7
14
7
7
7
0
20
7
7
7
7
0
20
% T
% Val:
14
0
0
7
0
0
0
14
7
14
0
7
14
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _